Uptake of branched-chain alpha-keto acids in <i>Bacillus subtilis</i>

نویسندگان

  • Barry J. Goldstein
  • Thomas Jefferson
  • Stanley A. Zahler
  • BARRY J. GOLDSTEIN
چکیده

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Biosynthesis of branched-chain fatty acids in Bacillus subtilis. A decarboxylase is essential for branched-chain fatty acid synthetase.

Branched long-chain fatty acids of the iso and anteiso series are synthesized in many bacteria from the branched-chain alpha-keto acids of valine, leucine, and isoleucine after their decarboxylation followed by chain elongation. Two distinct branched-chain alpha-keto acid (BCKA) and pyruvate decarboxylases, which are considered to be responsible for primer synthesis, were detected in, and purif...

متن کامل

Biosynthesis of branched-chain fatty acid in bacilli: FabD (malonyl-CoA:ACP transacylase) is not essential for in vitro biosynthesis of branched-chain fatty acids.

It was found that the partially purified beta-ketoacyl-ACP synthase of Bacillus insolitus did not require the addition of FabD (malonyl-CoA:ACP transacylase, MAT) for the activity assay. This study therefore examined the necessity of FabD protein for in vitro branched-chain fatty acid (BCFA) biosynthesis by crude fatty acid synthetases (FAS) of Bacilli. To discover the involvement of FabD in th...

متن کامل

Biosynthesis of Branched Chain Fatty Acids I. ISOLATION AND IDENTIFICATION Ol? FATTY ACIDS FROM BACILLUS SUBTILIS (ATCC 7059) *

S&o (1) has clearly identified the branched chain fatty acids, isopentadecanoic and isoheptadecanoic, in the lipids of Bacillus subtilis (natto). Another branched chain fatty acid, 12-methyltetradecanoic (sarcinic acid), has also been isolated from the lipids of a species of Surcina by Akashi and Saito (2). It is important to note that, these branched chain fatty acids occur in the bacterial li...

متن کامل

Biosythesis of branched chain fatty acids. I. Isolation and identification of fatty acids from Bacillus subtilis (ATCC 7059).

S&o (1) has clearly identified the branched chain fatty acids, isopentadecanoic and isoheptadecanoic, in the lipids of Bacillus subtilis (natto). Another branched chain fatty acid, 12-methyltetradecanoic (sarcinic acid), has also been isolated from the lipids of a species of Surcina by Akashi and Saito (2). It is important to note that, these branched chain fatty acids occur in the bacterial li...

متن کامل

Role of mitochondrial transamination in branched chain amino acid metabolism.

Oxidative decarboxylation and transamination of 1-14C-branched chain amino and alpha-keto acids were examined in mitochondria isolated from rat heart. Transamination was inhibited by aminooxyacetate, but not by L-cycloserine. At equimolar concentrations of alpha-ketoiso[1-14C]valerate (KIV) and isoleucine, transamination was increased by disrupting the mitochondria with detergent which suggests...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2017